Tlhaloso e Khutšoanyane:
Nomoro ea CAS: 126-07-8
Foromo ea molek'hule: C17H17ClO6
boima ba molek'hule: 352.77
Sebopeho sa lik'hemik'hale:
| Litaba tsa Motheo | |
| Lebitso la sehlahisoa | Griseofulvin |
| Kereiti | sehlopha sa meriana |
| Ponahalo | Phofo e tšoeu ho isa ho bosehla bo bosoeu |
| Tlhahlobo | 99% |
| Shelf bophelo | Lilemo tse 3 |
| Ho paka | 25kg / lebokose |
| Sebopeho | Ha e qhibilihe ka metsing, e qhibiliha ka bolokolohi ho dimethylformamide le tetrachloroethane, e qhibiliha hanyenyane ka ethanol e anhydrous le methanol. |
| Boemo | Boloka setshelo se kwetswe sebakeng se omileng, se nang le moya o motle. |
Tlhaloso ea kakaretso ea Griseofulvin
Griseofulvin ke sehlopha se seng sa polyene antifungal lithibela-mafu; e ka thibela ka matla mitosis ea fungal cell mme ea kena-kenana le motsoako oa DNA oa fungal; e ka boela ea tlama ho tubulin ho thibela karohano ea lisele tsa fungal. E 'nile ea sebelisoa ho meriana ea meriana ho tloha ka 1958' me hona joale e 'nile ea sebelisoa haholo bakeng sa ho phekola mafu a fungal a letlalo le stratum corneum e nang le liphello tse matla tsa inhibitory ho Trichophyton rubrum le Trichophyton tonsorans, joalo-joalo Griseofulvin ha se feela lithibela-mafu tse sebelisoang haholo bakeng sa bongaka. kalafo ea tšoaetso ea fungal ea letlalo le cuticle, empa hape e sebelisoa temong bakeng sa thibelo le kalafo ea mafu a fungal; mohlala, e na le katleho e khethehileng ea ho phekola mofuta oa candidiasis ka apole e ka bakang tšoaetso nakong ea ho tsamaisa peo.
Lipontšo tsa Griseofulvin
Ka meriana,sehlahiswa sena se loketse ho alafa mefuta e fapaneng ya seboko, ho kenyeletswa tinea capitis, tinea barbae, tinea ya mmele, jock itch, foot tinea le onychomycosis. Mefuta e fapaneng ea tinea e boletsoeng e bakoa ke li-fungus tse fapaneng tse kenyelletsang Trichophyton rubrum, Trichophyton tonsorans, Trichophyton mentagrophytes, Fingers Trichophyton, joalo-joalo, le Microsporon audouini, Microsporon canis, Microsporon gypseum le Epidermophyton floccosum, joalo-joalo. Sehlahisoa sena ha sea lokela ho phekoloa maemong a bobebe, maemong a ts'oaetso a sebakeng sa heno le linyeoe tse ka phekoloang ka li-antifungal agents. Griseofulvin ha e atlehe ho alafa tšoaetso ea mefuta e fapaneng ea li-fungus tse kang Candida, Histoplasma, Actinomyces, mefuta ea Sporothrix, Blastomyces, Coccidioides, Nocardio le Cryptococcus mefuta hammoho le ho phekola tinea versicolor.
Ka temo,sehlahisoa sena se qala ho hlahisoa ke Brian etal (1951) bakeng sa ho laola mafu a limela. Ho ea ka liphuputso tse fetileng, e ka sebelisoa bakeng sa thibelo ea lefu la melon (melon) sefate sa morara, lefu la ho ata ha lehapu, blight ea mahapu, anthracnose, blossom rot, apple cold rot, apple rot, cucumber downy mildew , hlobo ea fragola e bohlooho, likhahla tse leketlileng. , powdery hlobo ea lirosa, chrysanthemums powdery hlobo, rot flower lettuce, tomate blight ea pele, tulip fire blight le mafu a mang a fungal.
