Tlhaloso e Khutšoanyane:
Nomoro ea CAS: 24390-14-5
Foromo ea molek'hule: C24H31ClN2O9
boima ba molek'hule: 526.97
Sebopeho sa lik'hemik'hale:
| Litaba tsa Motheo | |
| Lebitso la sehlahisoa | Doxycycline hyclate |
| Kereiti | sehlopha sa meriana |
| Ponahalo | mosehla, phofo ea kristale ea hygroscopic |
| Tlhahlobo | 99% |
| Shelf bophelo | lilemo tse 2 |
| Ho paka | 25kg / lebokose |
| Boemo | bolokoa sebakeng se phodileng le se omileng |
Tlhaloso ea Doxycycline Hyclate
Doxycycline ke setho sa sehlopha sa lithibela-mafu tsa tetracycline, 'me hangata se sebelisetsoa ho phekola mafu a sa tšoaneng.Doxycycline hyclate ke phofo e mosehla, e nang le hygroscopic crystalline powder, e qhibilihang ka bolokolohi metsing le methanol, e qhibilihang ka mokhoa o fokolang ka ethanol (karolo ea 96 lekholong), e. e qhibiliha ka tharollo ea alkali hydroxides le carbonates.
Doxycycline Hyclate ke mofuta oa letsoai oa hyclate oa doxycycline, ke lithibela-mafu tse pharaletseng tsa tetracycline.E thibela motsoako oa protheine ea baktheria ka ho tlama li-ribosomes.Doxycycline e boetse e khetha ho thibela matrix metalloproteinase-8 (MMP-8) le MMP-13 holim'a MMP-1 ka 50, 60, le 5% inhibition, ka ho latellana, ha e sebelisoa ka bongata ba 30 μM.E ka sebelisoa e le molaoli oa tsamaiso ea liphatsa tsa lefutso tse inducible moo polelo e itšetlehileng ka ho ba teng (Tet-On) kapa ho ba sieo (Tet-Off) ea doxycycline.Metsoako e nang le doxycycline e 'nile ea sebelisoa ho phekola tšoaetso ea baktheria le thibelo ea malaria.
Tšebeliso ea "Doxycycline hyclate".
Doxycycline hyclate ke setho sa sehlopha sa lithibela-mafu sa tetracycline, 'me hangata se sebelisoa ho phekola mafu a sa tšoaneng.E sebelisoa ho phekola chlamydia, rickettsia, mycoplasma le mafu a mang a spirochete.E boetse e sebelisoa ho thibela matrix metalloproteinase ka tekanyo ea subantimicrobial.E thibela matrix metalloproteinase ka litekanyetso tsa subantimicrobial.
Doxycycline hyclate ke motsoako oa maiketsetso oa oxytetracycline.E 'nile ea sebelisoa ho felisa Borrelia burgdorferi le Anaplasma phagocytophilum matamong a litoeba le ho felisa liboseleise tsa Ixodes scapularis.Ke inhibitor e pharaletseng e sebelisetsoang ho thibela matrix metalloproteinases(MMP), joalo ka mofuta oa 1 collagenase lithutong tsa pholiso ea maqeba le tokiso ea lisele.
