Tlhaloso e Khutšoanyane:
Nomoro ea CAS: 24390-14-5
Foromo ea molek'hule: C24H31ClN2O9
boima ba molek'hule: 526.97
Sebopeho sa lik'hemik'hale:
| Litaba tsa Motheo | |
| Lebitso la sehlahisoa | Doxycycline hyclate |
| Kereiti | sehlopha sa meriana |
| Ponahalo | mosehla, phofo ea kristale ea hygroscopic |
| Tlhahlobo | 99% |
| Shelf bophelo | lilemo tse 2 |
| Ho paka | 25kg / lebokose |
| Boemo | bolokoa sebakeng se phodileng le se omileng |
Tlhaloso ea Doxycycline Hyclate
Doxycycline ke setho sa sehlopha sa lithibela-mafu sa tetracycline, 'me se atisa ho sebelisoa ho phekola mafu a sa tšoaneng.Doxycycline hyclate ke phofo e mosehla, ea hygroscopic crystalline, e qhibilihang ka bolokolohi metsing le methanol, e qhibilihang ka mokhoa o fokolang ka ethanol (karolo ea 96 lekholong), e. e qhibiliha ka tharollo ea alkali hydroxides le carbonates.
Doxycycline Hyclate ke mofuta oa letsoai oa hyclate oa doxycycline, ke lithibela-mafu tse pharaletseng tsa tetracycline. E thibela motsoako oa protheine ea baktheria ka ho tlama li-ribosomes. Doxycycline e boetse e khetha ho thibela motho matrix metalloproteinase-8 (MMP-8) le MMP-13 holim'a MMP-1 ka 50, 60, le 5% inhibition, ka ho latellana, ha e sebelisoa ka bongata ba 30 μM. E ka sebelisoa e le molaoli oa tsamaiso ea liphatsa tsa lefutso tse inducible moo polelo e itšetlehileng ka ho ba teng (Tet-On) kapa ho ba sieo (Tet-Off) ea doxycycline. Metsoako e nang le doxycycline e 'nile ea sebelisoa ho phekola tšoaetso ea baktheria le thibelo ea malaria.
Tšebeliso ea "Doxycycline hyclate".
Doxycycline hyclate ke setho sa sehlopha sa lithibela-mafu sa tetracycline, 'me hangata se sebelisoa ho phekola mafu a sa tšoaneng. E sebelisoa ho phekola chlamydia, rickettsia, mycoplasma le mafu a mang a spirochete. E boetse e sebelisoa ho thibela matrix metalloproteinase ka tekanyo ea subantimicrobial. E thibela matrix metalloproteinase ka litekanyetso tsa subantimicrobial.
Doxycycline hyclate ke motsoako oa maiketsetso oa oxytetracycline. E 'nile ea sebelisoa ho felisa Borrelia burgdorferi le Anaplasma phagocytophilum matamong a litoeba le ho felisa liboseleise tsa Ixodes scapularis. Ke inhibitor e pharaletseng e sebelisetsoang ho thibela matrix metalloproteinases(MMP), joalo ka mofuta oa 1 collagenase lithutong tsa pholiso ea maqeba le tokiso ea lisele.
