Litaba tsa Motheo | |
Lebitso la sehlahisoa | Theophylline Anhydrous |
Nomoro ea CAS. | 58-55-9 |
Ponahalo | bosoeu ho isa bosehla ba kristale powder |
Botsitso: | E tsitsitseng. Ha e lumellane le lisebelisoa tse matla tsa oxidizing. |
Ho qhibiliha ha Metsi | 8.3 g/L (20 ºC) |
Polokelo | 2-8°C |
Shelf Life | 2 Ylitsebe |
Sephutheloana | 25kg/ Moropa |
Tlhaloso ea Sehlahisoa
Theophylline ke methylxanthine e sebetsang joalo ka bronchodilator e fokolang. E na le thuso bakeng sa phekolo e sa foleng 'me ha e na thuso ho exacerbations e matla.
Theophylline ke methylxanthine alkaloid eo e leng inhibitor ea tlhōlisano ea phosphodiesterase (PDE; Ki = 100 μM). Hape ke mohanyetsi ea sa khetheng oa li-receptor tsa adenosine A (Ki = 14 μM bakeng sa A1 le A2). Theophylline e etsa hore ho be le phomolo ea feline bronchiole mesifa e boreleli e entsoeng esale pele ka acetylcholine (EC40 = 117 μM; EC80 = 208 μM). Meetso e nang le theophylline e sebelisitsoe kalafong ea asthma le lefu le sa foleng la matšoafo (COPD).
Kopo
1.Kalafo ea asthma: Theophylline e ka thusa ho kokobetsa matšoao a asthma ka ho atoloha liphasejeng tsa bronchial le ho eketsa phomolo ea mesifa.
2.Kalafo ea lefu la pelo: Theophylline e ka sebetsa e le vasodilator, e thusang ho ntlafatsa matšoao a lefu la pelo.
3.Tšusumetso ea tsamaiso ea methapo e bohareng: Theophylline e sebelisoa meriana e meng e le ntho e susumetsang tsamaiso ea methapo e bohareng, e khothalletsang ho falimeha le tlhokomelo.
4.Taolo ea metabolism ea mafura: Theophylline e ka khothalletsa ho senyeha ha mafura 'me ho lumeloa hore e thusa ho laola boima ba' mele le ho theola boima ba 'mele.