Tlhaloso e Khutšoanyane:
Nomoro ea CAS: 1405-10-3
Mokhoa oa molek'hule: C23H48N6O17S
Boima ba molek'hule: 712.72
Sebopeho sa lik'hemik'hale:
| Litaba tsa Motheo | |
| Lebitso la sehlahisoa | Neomycin sulfate |
| Nomoro ea CAS. | 1405-10-3 |
| Ponahalo | Phofo e tšoeu ho isa ho e mosehla hanyenyane |
| Kereiti | Sehlopha sa Pharma |
| Ho qhibiliha ha Metsi | E qhibilihang ka metsing |
| Polokelo | 2-8°C |
| Shelf Life | 2 Ylitsebe |
| Sephutheloana | 25kg/ Moropa |
Tlhaloso ea Sehlahisoa
Neomycin sulfate ke lithibela-mafu tsa aminoglycoside le calcium channel inhibitor ea protheine. Neomycin sulfate e boetse e tlama ho prokaryotic ribosomes e thibelang phetolelo mme e sebetsa kgahlanong le baktheria ya gram-positive le gram-negative. Neomycin sulfate e thibela PLC (Phospholipase C) ka ho tlama inositol phospholipids. E boetse e thibela ts'ebetso ea phosphatidylcholine-PLD mme e kenya ts'ebetso ea Ca2 + le ts'ebetso ea PLA2 ho liplatelete tsa batho. Neomycin sulfate e thibela ho senyeha ha DNA ea DNase I. E sebelisoa ho thibela kapa ho phekola mafu a letlalo a bakoang ke baktheria. Ha e sebetse khahlanong le mafu a fungal kapa kokoana-hloko.
Kopo
Neomycin sulfate ke lithibela-mafu tsa aminoglycoside tse hlahisoang ke S. fradiae tse thibelang phetolelo ea liprotheine ka ho tlama karolo e nyane ea li-ribosome tsa prokaryotic. E thibela likanale tsa Ca2+ tse nang le matla a motlakase 'me ke inhibitor e matla ea ho lokolloa ha masapo a mesifa ea sarcoplasmic reticulum Ca2 +. NEOMYCIN SULFATE e bontšitsoe ho thibela phetoho ea inositol phospholipid, phospholipase C, le phosphatidylcholine-phospholipase D mosebetsi (IC50 = 65 μM). E sebetsa haholo khahlanong le libaktheria tsa Gram-positive le Gram-negative 'me hangata e sebelisoa ho thibela tšoaetso ea baktheria ea meetlo ea lisele.
