Tlhaloso e Khutšoanyane:
Nomoro ea CAS: 1197-18-8
Foromo ea molek'hule: C8H15NO2
boima ba molek'hule: 157.21
Sebopeho sa lik'hemik'hale:
| Litaba tsa Motheo | |
| Lebitso la sehlahisoa | Tranexamic Acid |
| Kereiti | Cosmetic Grade |
| Ponahalo | E tšoeu kapa e batla e le tšoeu, phofo ea crystalline |
| Tlhahlobo | 99% |
| Shelf bophelo | lilemo tse 2 |
| Ho paka | 25kg / moropa |
| Lintho tsa Lik'hemik'hale | E qhibiliha ka bolokolohi metsing le ka har'a glacial acetic acid 'me e qhibiliha hanyenyane haholo ka har'a ethanol 'me e batla e sa qhibilihe ka har'a ether. |
Tlhaloso
Tranexamic acid e tsoa ho aminomethylbenzoic acid, le mofuta oa litlhare tsa antifibrinolytic ho emisa ho tsoa mali. Mokhoa oa hemostasis oa tranexamic acid o tšoana le aminocaproic acid le aminomethylbenzoic acid, empa phello e matla. Matla ke makhetlo a 7 ho isa ho a 10 a aminocaproic acid, makhetlo a 2 a aminomethylbenzoic acid, empa chefo e tšoana.
Sebopeho sa lik'hemik'hale tsa tranexamic acid se tšoana le lysine, inhibitive inhibition ea plasmin original in fibrin adsorption, ho thibela ts'ebetso ea bona, ho sireletsa protheine ea fiber hore e se ke ea senyeha ka plasmin le ho qhibiliha, qetellong e finyella hemostasis. E sebetsa kalafong ea fibrinolytic hyperthyroidism e matla kapa e sa foleng e bakoang ke ho tsoa mali, joalo ka ho tsoa mali, ho tsoa mali a renal, ho tsoa mali a prostate, hemophilia, pulmonary tuberculosis hemoptysis, ho tsoa mali ka mpeng kamora ts'ebetso ea sebete, matšoafo. , spleen le tse ling tse viscera hemorrhage; hape e ka sebelisoa ho buuoa ha ho tsoa mali a sa tloaelehang joalo-joalo.
Clinical tranexamic acid e na le phello e kholo ho mafu a ho longoa ke likokoanyana, dermatitis le eczema, purpura e bonolo, urticaria e sa foleng, urticaria ea maiketsetso ea thobalano, ho phatloha ho chefo le ho phatloha. Hape e na le phello e itseng ho erythroderma, scleroderma, systemic lupus erythematosus (SLE), Erythema multiforme, shingles le alopecia areata. Kalafo ea phello ea lefutso ea angioedema le eona e ntle. Kalafo ea Chloasma, meriana e akaretsang e sebetsa hoo e ka bang libeke tse 3, e sebetsa hantle libeke tse 5, nako ea matsatsi a 60. E fanoa ka molomo ka litekanyetso tsa 0.25 ~ 0.5 g, ka letsatsi 3 ~ 4 linako tse ling. Bakuli ba 'maloa ba ka ba le ho nyekeloa ke pelo, mokhathala, ho hlohlona, ho se thabise ka mpeng, le litla-morao ka mor'a hore matšoao a ho ikhula a nyamele.
Lipontšo
Ho tsoa mali ho fapaneng ho bakoang ke hyperfibrinolysis e matla kapa e sa foleng, ea sebakeng kapa ea systemic; boemo ba bobeli ba hyperfibrinolytic bo bakoang ke ho phatlalatsoa ha intravascular coagulation. Ka kakaretso u se ke ua sebelisa sehlahisoa sena pele ho heparinization.
Ho tsieleha kapa ho tsoa mali ka ho buuoa ka lisele le litho tse nang le li-activator tse ngata tsa plasminogen tse kang prostate, urethra, matšoafo, boko, popelo, litšoelesa tsa adrenal le qoqotho.
Mohanyetsi oa lithane tsa plasminogen activator (t-PA), streptokinase, le urokinase.
Fibrinolytic hemorrhage e bakoang ke ho ntšoa ha mpa ka maiketsetso, ho tsoa ha placenta pele ho nako, pelehi le amniotic fluid embolism; le ho eketseha ha menorrhagia e bakoang ke pathological intrauterine fibrinolysis.
Cerebral neuropathy ho tsoa mali hanyenyane, joalo ka subarachnoid hemorrhage le intracranial aneurysm hemorrhage, phello ea Amstat boemong bona e betere ho feta ea li-anti-fibrinolytic agents. Tlhokomelo e khethehileng e tlameha ho lefshoa kotsing ea cerebral edema kapa cerebral infarction.Ho bakuli ba matla ba nang le matšoao a ho buuoa, sehlahisoa sena se ka sebelisoa feela e le sethethefatsi se thusang.
Bakeng sa kalafo ea lefutso la angioneurotic edema, e ka fokotsa palo le ho teba ha liketsahalo.
E sebelisoa ho bakuli ba nang le hemophilia bakeng sa mali a bona a sebetsang hammoho le lithethefatsi tse ling.
Bakuli ba haemophilia ba nang le khaello ea factor VIII kapa factor IX ha ba ntša leino kapa ho buuoa ka molomo ha ba tsoa mali.
