Re itšetlehile ka matla a matla a theknoloji 'me re tsoela pele ho theha mahlale a tsoetseng pele ho khotsofatsa tlhoko ea Phepelo ea Boleng bo Botle 99%Powder e Hloekileng ea Albendazole, Lisebelisoa tsa Raw ea Liphoofolo, Re lula re labalabela ho theha likamano tse atlehileng tsa khoebo le bareki ba bacha lefatšeng ka bophara.
Re itšetlehile ka matla a matla a tekheniki 'me re lula re theha mahlale a tsoetseng pele ho khotsofatsa tlhoko eaChina Albendazole le Pharmaceutical Chemical, Khamphani ea rona e akaretsa sebaka sa 20, 000 square metres. Re na le basebetsi ba fetang 200, sehlopha sa litsebi tsa theknoloji, phihlelo ea lilemo tse 15, mosebetsi o tsoileng matsoho, boleng bo tsitsitseng le bo ka tšeptjoang, theko ea tlhōlisano le bokhoni bo lekaneng ba tlhahiso, ke kamoo re etsang hore bareki ba rona ba be matla. Haeba u na le lipotso, hopola ho se qeaqee ho iteanya le rona.
Tlhaloso
Albendazole (ALBENZA) ke anthelmintic e tsamaisoang ka molomo. Letlapa la Albendazole le hlafunoang le kenyelelitsoe lethathamong la Mokhatlo oa Lefatše oa Bophelo (WHO) la meriana ea bohlokoa e le moriana oa mala anthelminthic le antifilarial. Letlapa la Albendazole le entsoe ke SmithKline Animal Health Laboratories mme la amoheloa ke US Food and Drug Administration (FDA) ka 1996.
Albendazole e na le bokhoni ba ho bolaea mahe a whipworm le hookworm ka ho feletseng hammoho le ho bolaea mahe a Ascaris ka mokhoa o sa fellang; e ka boela ea felisa mefuta e fapaneng ea li-nematode tse tšoaetsanoang ka har'a 'mele ea liphoofolo, 'me e na le liphello tsa ho felisa kapa ho bolaea tapeworms le cysticerci ka ho toba. Ka hona, e thusa ho phekola hydatid le tsamaiso ea methapo (cysticercosis) e bakoang ke tšoaetso ea seboko sa nama ea kolobe, hape le kalafo ea hookworm, roundworm, pinworm, nematode trichinella, tapeworm, whipworm le stercoralis nematode.
Pharmacodynamics
Albendazole ke mofuta o tsoang ho benzimidazole. E kenngoa ka potlako ka har'a vivo ho sulfoxide, sulfone le 2-polyamine sulfone alcohol. E ka hatella ka mokhoa o ikhethileng le ka mokhoa o ke keng oa thijoa ho ts'oaroa ha tsoekere ea li-nematode tsa mala, ka hona ho fella ka ho fokotseha ha glycogen ea seboko; ka nako e ts'oanang, e boetse e thibela mosebetsi oa fumarate reductase, 'me kahoo e thibela moloko oa adenosine triphosphate, qetellong e baka lefu la likokoana-hloko.
E ts'oanang le mebendazole, ka ho baka denaturation ea cytoplasmic microtubules ea likokoana-hloko tsa mala le ho tlama ho tubulin, e baka ho koala ha lipalangoang tsa intracellular, ho baka ho bokella likaroloana tsa Golgi endocrine; cytoplasm e tsoela pele ho qhibiliha butle-butle, e leng se bakang lefu la ho qetela la likokoana-hloko.
Sehlahisoa sena se ka bolaea mahe a hookworm ka ho feletseng, mahe a pinworm, mahe a spinworm, mahe a tapeworm le mahe a shapa a cysticercosis 'me a bolaea mahe a Ascaris ka mokhoa o fokolang.
Tšebeliso e Tloaelehileng
Albendazole ke moriana o sebelisetsoang ho phekola mafu a bakoang ke likokoana-hloko. E ka fuoa ho phekola tšoaetso e sa tloaelehang ea boko (neurocysticercosis) kapa e ka fuoa ho phekola tšoaetso ea likokoana-hloko e bakang letšollo la bohlokoa (microsporidiosis).
Tšebeliso ea Clinical
Albendazole e na le tšebetso e pharaletseng khahlanong le nematodes le cestodes ea mala, hammoho le li-flukes tsa sebete Opisthorchis sinensis, Opisthorchis viverrini, le Clonorchis sinensis. E boetse e sebelisitsoe ka katleho khahlanong le Giardia lamblia. E sebelisoa haholo lefatšeng ka bophara bakeng sa kalafo ea tšoaetso ea intestinalnematode. E sebetsa hantle joalo ka kalafo ea lethal le le leng bakeng sa ascariasis, tšoaetso ea hookworm ea Lefatše le Lecha le la Khale, le trichuriasis. Phekolo ea litekanyetso tse ngata ka albendazole caneradicate pinworm, threadworm, capillariasis, clonorchiasis, le lefu la hydatid. Katleho ea albendazole khahlano le liboko tsa tapeworms (cestodes) hangata e fetoha ebile ha e khahlise haholo. E boetse e sebetsa hantle ho alafang cerebral le spinal neurocysticercosis, haholo-holo ha e fanoa ka dexamethasone.Albendazole e buelloa bakeng sa phekolo ea gnathostomiasis.
Re itšetlehile ka matla a matla a theknoloji 'me re tsoela pele ho theha mahlale a tsoetseng pele ho khotsofatsa tlhoko ea Phepelo ea Boleng bo Botle 99%Powder e Hloekileng ea Albendazole, Lisebelisoa tsa Raw ea Liphoofolo, Re lula re labalabela ho theha likamano tse atlehileng tsa khoebo le bareki ba bacha lefatšeng ka bophara.
Boleng bo botleChina Albendazole le Pharmaceutical Chemical, Khamphani ea rona e akaretsa sebaka sa 20, 000 square metres. Re na le basebetsi ba fetang 200, sehlopha sa litsebi tsa theknoloji, phihlelo ea lilemo tse 15, mosebetsi o tsoileng matsoho, boleng bo tsitsitseng le bo ka tšeptjoang, theko ea tlhōlisano le bokhoni bo lekaneng ba tlhahiso, ke kamoo re etsang hore bareki ba rona ba be matla. Haeba u na le lipotso, hopola ho se qeaqee ho iteanya le rona.