Cefazolin sodium letsoai

Sethibela-mafu sa semi synthetic se nang le cephalosporins molek'hule ea cephalosporins. E fetoletsoe joalo ka Xianfeng mycin. ke ea β－Likokoana-hloko tsa Lactam, e, β- Li-derivatives tsa 7-aminocephalosporanic acid (7-ACA) ka har'a lithibela-mafu tsa lactam li na le mekhoa e tšoanang ea bactericidal. Mofuta ona oa meriana o ka senya lerako la sele ea libaktheria 'me oa li bolaea nakong ea pelehi. E na le phello e matla ea ho khetha libaktheria 'me e batla e se na chefo ho batho, e na le melemo e kang ea antibacterial spectrum, matla a antibacterial, ho hanyetsa li-enzyme tsa penicillin, le ho fokotseha ho fokolang ha ho bapisoa le penicillin. Kahoo ke lithibela-mafu tsa bohlokoa tse nang le ts'ebetso e phahameng, chefo e tlase, le ts'ebeliso e pharaletseng ea bongaka. Li-cephalosporins tsa moloko oa pele li entsoe pejana, ka ts'ebetso e matla ea antibacterial ha e bapisoa le Chemicalbook, antibacterial spectrum e nyane, le litlamorao tse ntle tsa anti Gram positive ho feta libaktheria tsa Gram. E hlahiswa ke Staphylococcus aureus β- Lactamase e tsitsitse mme e ka thibela tlhahiso ya baktheria e mpe β- Lactamase ha e tsitsa mme e ntse e ka hlahiswa ke dibaktheria tse ngata tsa Gram negative β- Se senyehileng ke lactamase. Cefazolin sodium ke semi synthetic moloko oa pele oa cephalosporin e nang le litlamorao tsa antibacteria khahlano le libaktheria tse ntle tsa gram le gram-negative. E sebelisoa ka tloaelo ho mafu a tsamaiso ea ho hema, tsamaiso ea urogenital, letlalo le bonolo la letlalo, lesapo le lenonyeletso, le pampitšana ea biliary e bakoang ke libaktheria tse nang le kutloelo-bohloko, hammoho le endocarditis, sepsis, pharyngeal le mafu a litsebe. E na le ts'ebetso e matla khahlanong le libaktheria tsa gram-positive tse kang Staphylococcus aureus le Streptococcus (ntle le Enterococcus), 'me e phahametse ea bobeli ea moloko oa Boraro oa cephalosporins.